The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 25, 2021

Filed:

Aug. 27, 2018
Applicant:

The Board of Regents of the University of Texas System, Austin, TX (US);

Inventors:

Jinming Gao, Plano, TX (US);

Gang Huang, Plano, TX (US);

Tian Zhao, Irving, TX (US);

Xinpeng Ma, Dallas, TX (US);

Yiguang Wang, Dallas, TX (US);

Yang Li, Dallas, TX (US);

Baran D. Sumer, Dallas, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/00 (2006.01); C09B 69/10 (2006.01); G01N 33/84 (2006.01); G01N 33/58 (2006.01); G01N 21/64 (2006.01); C08F 8/42 (2006.01); C08F 8/34 (2006.01); C08F 8/32 (2006.01); C08F 8/30 (2006.01);
U.S. Cl.
CPC ...
A61K 49/0054 (2013.01); A61K 49/0021 (2013.01); A61K 49/0032 (2013.01); A61K 49/0041 (2013.01); C08F 8/30 (2013.01); C08F 8/32 (2013.01); C08F 8/34 (2013.01); C08F 8/42 (2013.01); C09B 69/103 (2013.01); C09B 69/105 (2013.01); C09B 69/106 (2013.01); C09B 69/109 (2013.01); G01N 21/643 (2013.01); G01N 21/6428 (2013.01); G01N 21/6456 (2013.01); G01N 33/582 (2013.01); G01N 33/84 (2013.01); G01N 2021/6432 (2013.01); G01N 2021/6439 (2013.01); G01N 2021/6441 (2013.01);
Abstract

The present disclosure relates to polymers which contain a hydrophobic and hydrophilic segment which is sensitive to pH. In some aspects, the polymers form a micelle which is sensitive to pH and results in a change in fluorescence based upon the particular pH. In some aspects, the disclosure also provides methods of using the polymers for the imaging of cellular or extracellular environment or delivering a drug.


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