The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 25, 2021

Filed:

Dec. 07, 2016
Applicant:

Hoffmann-la Roche Inc., Little Falls, NJ (US);

Inventors:

Marina Bacac, Schlieren, CH;

Stefan Evers, Schlieren, CH;

Christian Klein, Schlieren, CH;

Pavel Pisa, Schlieren, CH;

Eva Rossmann, Basel, CH;

Jose Saro, Schlieren, CH;

Pablo Umana, Schlieren, CH;

Assignee:

Hoffmann-La Roche Inc., Little Falls, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/395 (2006.01); C07K 16/30 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39558 (2013.01); A61K 39/3955 (2013.01); A61K 39/39583 (2013.01); C07K 16/2809 (2013.01); C07K 16/2887 (2013.01); C07K 16/3007 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); A61K 2039/54 (2013.01); A61K 2039/545 (2013.01); C07K 2317/31 (2013.01); C07K 2319/00 (2013.01); C07K 2319/24 (2013.01);
Abstract

The present invention relates to methods of treating a disease, and methods for reduction of the formation of anti-drug antibodies (ADAs) in response to the administration of a therapeutic agent. The invention further relates to methods of treating a disease, particularly a B-cell proliferative disorder, and methods for reduction of adverse effects in response to the administration of a therapeutic agent, particularly a T-cell activating therapeutic agent.


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