The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 25, 2021

Filed:

Jun. 09, 2020
Applicants:

The Board of Trustees of the University of Arkansas, Little Rock, AR (US);

The Texas A&m University System, College Station, TX (US);

Inventors:

Lisa Bielke, Wooster, OH (US);

Sherryll Layton, Rogers, AR (US);

Billy Hargis, Fayetteville, AR (US);

Neil R. Pumford, Bentonville, AR (US);

Olivia B. Faulkner, Shawnee, KS (US);

Luc Berghman, College Station, TX (US);

Daad Abi-Ghanem, Tigard, OR (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/02 (2006.01); C07H 21/02 (2006.01); A61K 39/112 (2006.01); A61K 39/108 (2006.01); C07K 16/12 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0275 (2013.01); A61K 39/0258 (2013.01); A61K 39/105 (2013.01); A61K 39/107 (2013.01); C07K 16/1232 (2013.01); C12N 15/85 (2013.01); A61K 2039/523 (2013.01); A61K 2039/53 (2013.01); C07K 2317/34 (2013.01); Y02A 50/30 (2018.01);
Abstract

Vaccine vectors capable of eliciting an immune response to enteric bacteria and methods of using the same are provided. The vaccine vectors include a polynucleotide encoding a PAL polypeptide. The PAL polypeptide may be expressed on the surface of the vaccine vector. The vaccine vector may also include a second polypeptide encoding an immunostimulatory polypeptide such as a CD154 polypeptide or an HMGB1 polypeptide.


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