The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 25, 2021

Filed:

Aug. 29, 2018
Applicants:

Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, CN;

Suzhou Suplead Life Sciences Co., Ltd., Jiangsu, CN;

Inventors:

Bing Zhou, Shanghai, CN;

Cheng Luo, Shanghai, CN;

Yaxi Yang, Shanghai, CN;

Yuanyuan Zhang, Shanghai, CN;

Daohai Du, Shanghai, CN;

Hualiang Jiang, Shanghai, CN;

Gang Qiao, Jiangsu, CN;

Xinjun Wang, Jiangsu, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); C07D 487/04 (2013.01);
Abstract

The present invention provides a compound represented by formula I, pharmaceutically acceptable salts, enantiomers, diastereomers or racemates thereof, the preparation method thereof, the pharmaceutical composition comprising the same, and the use thereof in the preparation of a medicament for treating a disease or condition mediated by EED and/or PRC2. The compound of the present invention can be used treating PRC2-mediated diseases or conditions.


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