The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 25, 2021

Filed:

Jul. 30, 2019
Applicant:

Forma Therapeutics, Inc., Watertown, MA (US);

Inventors:

Patrick F. Kelly, Concord, MA (US);

Alan Collis, Lexington, MA (US);

Jeff Davis, Hingham, MA (US);

Duncan Walker, Boulder, CO (US);

Susan Ashwell, Carlisle, MA (US);

Blythe Thomson, Cincinnati, OH (US);

Wei Lu, Newton, MA (US);

Assignee:

FORMA Therapeutics, Inc., Watertown, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4709 (2006.01); A61P 35/02 (2006.01); C12Q 1/686 (2018.01); C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
A61K 31/4709 (2013.01); A61P 35/02 (2018.01); C12Q 1/686 (2013.01); C12Q 1/6886 (2013.01); C12Q 2531/113 (2013.01); C12Q 2561/113 (2013.01); C12Q 2600/156 (2013.01);
Abstract

Methods of treating patients diagnosed with AML or MDS harboring mutant IDH-1 include detecting an IDH1 mutation and the therapeutic administration of an inhibitor of a mutant IDH-1 as a single agent, or in combination with azacitidine (AZA) or cytarabine.


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