The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 25, 2021
Filed:
Jun. 04, 2019
Applicant:
Forma Therapeutics, Inc., Watertown, MA (US);
Inventors:
Susan Ashwell, Carlisle, MA (US);
Blythe Thomson, Cincinnati, OH (US);
Patrick F. Kelly, Concord, MA (US);
Alan Collis, Lexington, MA (US);
Jeff Davis, Hingham, MA (US);
Duncan Walker, Boulder, CO (US);
Wei Lu, Newton, MA (US);
Assignee:
FORMA Therapeutics, Inc., Watertown, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4709 (2006.01); A61K 31/706 (2006.01); A61P 35/02 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4709 (2013.01); A61K 31/706 (2013.01); A61P 35/00 (2018.01); A61P 35/02 (2018.01);
Abstract
Patients diagnosed with a cancer harboring an IDH-1 mutation can be treated by the administration of a therapeutically effective amount of a pharmaceutical composition comprising Compound 1, a selective inhibitor of 2-HG production from mIDH-1 enzymes including the R132 mutations R132C, R132H, R132L, R132G, and R132S.