The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 25, 2021

Filed:

Jan. 10, 2018
Applicant:

Gruenenthal Gmbh, Aachen, DE;

Inventors:

Marc Schiller, Aachen, DE;

Carlos van Hemelrijck, Aachen, DE;

Stefanie Straub, Bad Vilbel, DE;

Eva Wulsten, Willich, DE;

Ulrike Bertram, Aachen, DE;

Ulrich Reinhold, Aachen, DE;

Assignee:

Grünenthal GmbH, Aachen, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/12 (2006.01); A61K 31/137 (2006.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61P 25/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/137 (2013.01); A61K 9/0019 (2013.01); A61K 9/08 (2013.01); A61K 47/12 (2013.01); A61P 25/04 (2018.01);
Abstract

The invention relates to an aqueous pharmaceutical composition for parenteral administration comprising Tapentadol or a physiologically acceptable salt thereof, wherein the concentration of Tapentadol is within the range of from 0.10 to 8.00 mg/mL, based on the weight of Tapentadol free base and based on the total volume of the composition; and wherein the pH value of the composition is buffered and within the range of from 4.0 to 6.0. The invention also relates to a container comprising the pharmaceutical composition and a process for the preparation thereof. The invention also relates to a kit comprising the contained according to the invention in a packaging. The pharmaceutical composition according to the invention is particularly useful for treating pain, especially acute pain, preferably in pediatric patients.


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