The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 25, 2021
Filed:
Aug. 12, 2019
Applicant:
Novartis Ag, Basel, CH;
Inventors:
Luis Brito, Cambridge, MA (US);
Delai Chen, Cambridge, MA (US);
Gabriel Grant Gamber, Cambridge, MA (US);
Andrew Geall, Cambridge, MA (US);
Kevin Love, Somerville, MA (US);
Thomas Zabawa, Cambridge, MA (US);
Frederic Zecri, Cambridge, MA (US);
Assignee:
Novartis AG, Basel, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 319/06 (2006.01); C07C 219/06 (2006.01); C07C 229/12 (2006.01); C07D 207/12 (2006.01); C07D 207/16 (2006.01); C07D 211/22 (2006.01); C07D 211/62 (2006.01); C07C 323/52 (2006.01); A61K 31/7105 (2006.01); A61K 31/713 (2006.01); C07C 219/16 (2006.01); C07D 233/60 (2006.01); C07D 295/088 (2006.01); C12N 15/88 (2006.01); A61K 9/51 (2006.01); A61K 9/127 (2006.01); A61K 47/18 (2017.01); A61K 38/18 (2006.01); A61K 38/22 (2006.01); A61K 39/12 (2006.01); C07C 235/08 (2006.01); C07D 211/06 (2006.01); C07D 211/46 (2006.01); C07D 233/64 (2006.01); C07D 295/13 (2006.01); C12N 7/00 (2006.01); C12N 15/113 (2010.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5123 (2013.01); A61K 9/1272 (2013.01); A61K 31/713 (2013.01); A61K 31/7105 (2013.01); A61K 38/1816 (2013.01); A61K 38/2264 (2013.01); A61K 39/12 (2013.01); A61K 47/18 (2013.01); C07C 219/06 (2013.01); C07C 219/16 (2013.01); C07C 229/12 (2013.01); C07C 235/08 (2013.01); C07C 323/52 (2013.01); C07D 207/12 (2013.01); C07D 207/16 (2013.01); C07D 211/06 (2013.01); C07D 211/22 (2013.01); C07D 211/46 (2013.01); C07D 211/62 (2013.01); C07D 233/60 (2013.01); C07D 233/64 (2013.01); C07D 295/088 (2013.01); C07D 295/13 (2013.01); C07D 319/06 (2013.01); C12N 7/00 (2013.01); C12N 15/1137 (2013.01); C12N 15/88 (2013.01); A61K 2039/53 (2013.01); C12N 2310/14 (2013.01); C12N 2320/32 (2013.01); C12N 2760/00034 (2013.01); C12N 2760/00071 (2013.01);
Abstract
This invention provides for a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein R-R, n, p, Land Lare defined herein. The compounds of formula (I) and pharmaceutically acceptable salts thereof are cationic lipids useful in the delivery of biologically active agents to cells and tissues.