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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11013694 B1

PDFFull Text
Date of Patent:
May. 25, 2021

Filed:

May. 24, 2019

Formulation of a micro drop pill and the preparation method thereof

Applicant:

Tasly Pharmaceutical Group Co., Ltd., Tianjin, CN;

Inventors:

Xijun Yan, Tianjin, CN;

Naifeng Wu, Tianjin, CN;

Kaijing Yan, Tianjin, CN;

Xiaobing Sun, Tianjin, CN;

Shunnan Zhang, Tianjin, CN;

Zhengliang Ye, Tianjin, CN;

Hai'ou Dong, Tianjin, CN;

Hongbo Zhang, Tianjin, CN;

Wensheng Zhang, Tianjin, CN;

Lihong Zhou, Tianjin, CN;

Chenming Li, Tianjin, CN;

Cong Chen, Tianjin, CN;

Xiaofeng Liu, Tianjin, CN;

Shiqing Wang, Tianjin, CN;

Changsheng Rong, Tianjin, CN;

Yongfeng Zheng, Tianjin, CN;

Lijun Fan, Tianjin, CN;

Assignee:

TASLY PHARMACEUTICAL GROUP CO., LTD., Tianjin, CN;

Attorney:

Klarquist Sparkman, LLP

Primary Examiner:

Gina C Justice

Int. Cl.
CPC ...
A61K 9/20 (2006.01); A61K 36/537 (2006.01); A61K 36/258 (2006.01); A61K 45/06 (2006.01); A61J 3/06 (2006.01); A61K 9/50 (2006.01); A61K 36/48 (2006.01); A61K 36/481 (2006.01);
U.S. Cl.
CPC ...
A61K 9/2095 (2013.01); A61J 3/06 (2013.01); A61K 9/2027 (2013.01); A61K 9/2054 (2013.01); A61K 9/2059 (2013.01); A61K 9/5015 (2013.01); A61K 9/5026 (2013.01); A61K 9/5042 (2013.01); A61K 9/5089 (2013.01); A61K 36/258 (2013.01); A61K 36/48 (2013.01); A61K 36/481 (2013.01); A61K 36/537 (2013.01); A61K 45/06 (2013.01);
Abstract

The present invention relates to a preparation method for a traditional Chinese medicine drop pill and a traditional Chinese medicine micro drop pill prepared by using the method, and in particular, the present invention relates to a micro drop pill preparation method with high drug-loading capacity, simple preparation process and high production rate and a micro drop pill prepared by using the method. Specially, The drop pill preparation method used comprises the following steps: (1) material melting step: heat melting a medicine and a drop pill matrix to obtain a molten medicine liquid; (2) dropping step: delivering the molten medicine liquid to a dripper, and acquiring medicine drops of the molten medicine liquid by means of vibration dropping; and, (3) condensation step: cooling the medicine drops with a cooling gas to obtain micro drop pills.

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