The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 25, 2021

Filed:

May. 03, 2018
Applicants:

Repairogen Corp, Ithaca, NY (US);

University of Louisville Research Foundation, Inc., Louisville, KY (US);

Cornell University, Ithaca, NY (US);

Inventors:

Michael Boice, San Mateo, CA (US);

Frank Borchetta, New Rochelle, NY (US);

Albert Cunningham, Crestwood, KY (US);

John Trent, Louisville, KY (US);

Pengbo Zhou, Princeton Junction, NJ (US);

Chenyi Yang, Rego Park, NY (US);

Assignees:

Repairogen Corp., Ithaca, NY (US);

University of Louisville Research Foundation, Inc., Louisville, KY (US);

Cornell University, Ithaca, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 8/35 (2006.01); A61K 8/44 (2006.01); A61K 8/49 (2006.01); A61K 31/353 (2006.01); A61K 31/122 (2006.01); A61Q 19/08 (2006.01); A61Q 19/00 (2006.01); A61Q 1/00 (2006.01); A61Q 15/00 (2006.01); A61Q 17/04 (2006.01); A61Q 19/10 (2006.01); A61Q 5/02 (2006.01); A61Q 19/04 (2006.01); A61Q 1/02 (2006.01);
U.S. Cl.
CPC ...
A61K 8/355 (2013.01); A61K 8/35 (2013.01); A61K 8/44 (2013.01); A61K 8/49 (2013.01); A61K 8/498 (2013.01); A61K 31/122 (2013.01); A61K 31/353 (2013.01); A61Q 1/00 (2013.01); A61Q 15/00 (2013.01); A61Q 19/007 (2013.01); A61Q 19/08 (2013.01); A61Q 1/02 (2013.01); A61Q 5/02 (2013.01); A61Q 17/04 (2013.01); A61Q 19/04 (2013.01); A61Q 19/10 (2013.01);
Abstract

Described are compositions containing quinones that show activity in enhance DNA repair and/or prevent damage to DNA and/or upregulate genes associated with wound healing. The quinones are thymoquinone, lapachol, myrtucommulone C, or mixtures thereof, and can be formulated into cosmetic compositions for topical administration to a subject in need thereof. The cosmetic compositions can also include sunscreens, surfactants, sunless tanning agents, desquamation agents, antiperspirants, colorants, preservatives and mixtures; and a cosmetically acceptable carrier. The compositions should find use in methods for treating the signs of ageing in mammals, dermatitis and wound healing via topical application to a site in need thereof, such as the skin or hair of the mammals or a wound site.


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