The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 18, 2021

Filed:

Dec. 01, 2015
Applicant:

Cornell University, Ithaca, NY (US);

Inventors:

Jonathan Alden, Ithaca, NY (US);

Alejandro Cortese, Ithaca, NY (US);

Arthur Barnard, Hayward, CA (US);

Paul McEuen, Newfield, NY (US);

Assignee:

Cornell University, Ithaca, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/487 (2006.01); G01N 33/543 (2006.01); C12Q 1/6869 (2018.01); G01N 27/414 (2006.01); G01N 27/447 (2006.01);
U.S. Cl.
CPC ...
G01N 33/48721 (2013.01); C12Q 1/6869 (2013.01); G01N 27/4145 (2013.01); G01N 27/4146 (2013.01); G01N 27/44791 (2013.01); G01N 33/54366 (2013.01);
Abstract

A nanopore-containing substrate includes a substrate, a membrane on the substrate, and at least one nanoscale electronic element disposed on or embedded in the membrane. The membrane defines at least one nanopore. The nanoscale electronic element is aligned with one of the nanopores such that a shortest distance between an edge of the nanoscale electronic element and the edge of the nanopore is less than 50 nm. The nanopores may be formed by etching through a dielectric layer using a solution while applying a voltage to the nanoscale electronic element relative to the solution. The nanopore-containing substrate can be used to detect or sequence a biopolymer, such as a nucleic acid. The nanopore-containing substrate may be used with a biopolymer detection and/or sequencing system.


Find Patent Forward Citations

Loading…