The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 18, 2021
Filed:
Oct. 17, 2018
Applicant:
Dicerna Pharmaceuticals, Inc., Lexington, MA (US);
Inventor:
Shanthi Ganesh, Shrewsbury, MA (US);
Assignee:
Dicerna Pharmaceuticals, Inc., Lexington, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 15/113 (2010.01); A61P 35/00 (2006.01); A61K 9/00 (2006.01); A61K 9/127 (2006.01); A61K 9/51 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 9/0019 (2013.01); A61K 9/127 (2013.01); A61K 9/51 (2013.01); A61P 35/00 (2018.01); C12N 2310/11 (2013.01); C12N 2310/321 (2013.01); C12N 2310/322 (2013.01);
Abstract
Provided herein is a potent, optimized β-catenin nucleic acid inhibitor molecule with a unique pattern of modified nucleotides. Also provided are methods and compositions for reducing β-catenin expression and methods and compositions for treating cancer.