The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 18, 2021
Filed:
Jul. 27, 2016
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Dongeun Huh, Villanova, PA (US);
Mark Mondrinos, Philadelphia, PA (US);
Cassidy Blundell, Cambridge, MA (US);
Jeongyun Seo, Philadelphia, PA (US);
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, Philadelphia, PA (US);
Abstract
The presently disclosed subject matter provides an approach to address the needs for microscale control in shaping the spacial geometry and microarchitecture of 3D collagen hydrogels. For example, the disclosed subject matter provides for compositions, methods, and systems employing N-sulfosuccinimidyl-6-(4'-azido-2′-nitro-phenylamino)hexanoate ('sulfo-SANPAH'), to prevent detachment of the hydrogel from the anchoring substrate due to cell-mediated contraction.