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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11008400 B1

PDFFull Text
Expired
Date of Patent:
May. 18, 2021

Filed:

Nov. 24, 2016

Anti-5t4 antibodies and antibody-drug conjugates

Applicant:

Byondis B.v., Nijmegen, NL;

Inventors:

Miranda Maria Cornelia Van der Lee, Nijmegen, NL;

Gerardus Joseph Andreas Ariaans, Nijmegen, NL;

Jan Schouten, Nijmegen, NL;

Marion Blomenrohr, Nijmegen, NL;

Patrick Gerhard Groothuis, Nijmegen, NL;

Rudy Gerardus Elisabeth Coumans, Nijmegen, NL;

Assignee:

Byondis B.V., Nijmegen, NL;

Attorney:

Buscher Patent PLLC

Primary Examiner:

Karl J Puttlitz

Int. Cl.
CPC ...
C07K 16/32 (2006.01); C07K 16/30 (2006.01); A61K 47/60 (2017.01); A61K 47/54 (2017.01); A61K 47/68 (2017.01); A61K 39/44 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); A61K 31/437 (2006.01);
U.S. Cl.
CPC ...
C07K 16/32 (2013.01); A61K 31/437 (2013.01); A61K 39/44 (2013.01); A61K 45/06 (2013.01); A61K 47/546 (2017.08); A61K 47/60 (2017.08); A61K 47/6803 (2017.08); A61K 47/6851 (2017.08); A61K 47/6889 (2017.08); A61P 35/00 (2018.01); C07K 16/30 (2013.01); C07K 2317/34 (2013.01); C07K 2317/92 (2013.01);
Abstract

The present disclosure relates to CDR defined antibodies targeting the 5T4 oncofoetal antigen (TPBG, 5T4, Wnt Activated Inhibitory Factor 1, WAIF1) which exhibit a binding affinity for human 5T4 antigen which is in the same order of magnitude as their affinity for cynomolgus monkey 5T4. Antibody-drug conjugates (ADCs), and their use in the treatment of human solid tumours and haematological malignancies are claimed.

Find Patent Forward Citations

Van der Lee, Miranda Maria Cornelia. (2021). Anti-5t4 antibodies and antibody-drug conjugates (U.S. Patent No. 11008400). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11008400

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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