The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 18, 2021

Filed:

Jan. 21, 2020
Applicant:

Bristol Myers-squibb Company, Princeton, NJ (US);

Inventors:

Aaron Paul Yamniuk, Lawrenceville, NJ (US);

Scott Ronald Brodeur, New Hope, PA (US);

Ekaterina Deyanova, Lawrenceville, NJ (US);

Richard Yu-Cheng Huang, Bridgewater, NJ (US);

Yun Wang, Plainsboro, NJ (US);

Alfred Robert Langish, Feasterville, PA (US);

Guodong Chen, East Brunswick, NJ (US);

Stephen Michael Carl, Howell, NJ (US);

Hong Shen, Belle Mead, NJ (US);

Achal Mukundrao Pashine, Mahwah, NJ (US);

Lin Hui Su, Somerville, MA (US);

Assignee:

Bristol Myers-Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61P 29/00 (2006.01); C12N 15/63 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2866 (2013.01); A61P 29/00 (2018.01); C12N 15/63 (2013.01); A61K 2039/505 (2013.01); C07K 2317/565 (2013.01);
Abstract

Provided herein are antibodies that bind to the alpha subunit of an IL-7 receptor (IL-7Rα). Also provided are uses of these antibodies in therapeutic applications, such as treatment of inflammatory diseases. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain regions of the antibodies, and vectors comprising the polynucleotides.


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