The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 18, 2021

Filed:

May. 29, 2019
Applicant:

Turning Point Therapeutics, Inc., San Diego, CA (US);

Inventors:

Jingrong J. Cui, San Diego, CA (US);

Yishan Li, San Diego, CA (US);

Evan W. Rogers, San Diego, CA (US);

Dayong Zhai, San Diego, CA (US);

Wei Deng, San Diego, CA (US);

Jane Ung, San Diego, CA (US);

Assignee:

Turning Point Therapeutics, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/407 (2006.01); A61K 31/4353 (2006.01); C07D 209/56 (2006.01); C07D 221/22 (2006.01); C07D 498/22 (2006.01); C07D 498/14 (2006.01);
U.S. Cl.
CPC ...
C07D 498/22 (2013.01); C07D 498/14 (2013.01);
Abstract

The present disclosure relates to certain chiral diaryl macrocyclic derivatives, of the formula I: pharmaceutical compositions containing them, and methods of using them to treat cancer, pain, neurological diseases, autoimmune diseases, and inflammation.


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