The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 18, 2021

Filed:

Sep. 01, 2017
Applicant:

Institute of Radiation Medicine Chinese Academy of Medical Sciences, Tianjin, CN;

Inventors:

Hongqi Tian, Tianjin, CN;

Ying Cheng, Tianjin, CN;

Qianru Zhang, Tianjin, CN;

Zhimei Zhu, Tianjin, CN;

Yueying Wang, Tianjin, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 323/44 (2006.01); C07C 321/04 (2006.01); C07C 319/12 (2006.01); C07C 319/06 (2006.01); C07C 323/25 (2006.01); A61P 39/02 (2006.01); A61P 35/00 (2006.01); A61K 31/16 (2006.01);
U.S. Cl.
CPC ...
C07C 323/44 (2013.01); A61K 31/16 (2013.01); A61P 35/00 (2018.01); A61P 39/02 (2018.01); C07C 319/06 (2013.01); C07C 319/12 (2013.01); C07C 321/04 (2013.01); C07C 323/25 (2013.01);
Abstract

The present invention discloses an amino mercaptan compound, preparation method thereof and use thereof in radiation protection. The compound has the structure of formula I, wherein A, A, R, R, R, R, and Rand Rare defined herein. The compound has the effects of reducing the biological damage caused by ionizing radiation, extending the survival period and survival rate of the radiated animals, and significantly alleviating the side effects of radiotherapy, and has a low toxicity. The present invention opens up a new way for protection and treatment of ionizing radiation damage.


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