The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 18, 2021

Filed:

Aug. 14, 2015
Applicants:

Medimmune, Llc, Gaithersburg, MD (US);

The Regents of the University of California, Santa Barbara, CA (US);

Inventors:

Andrew Csordas, Santa Barbara, CA (US);

James B. McGivney IV, Gaithersburg, MD (US);

Hyongsok Tom Soh, Santa Barbara, CA (US);

Robert Strouse, Gaithersburg, MD (US);

Faye Walker, Santa Barbara, CA (US);

Assignees:

Medlmmune, LLC, Gaithersburg, MD (US);

The Regents of the University of California, Santa Barbara, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07H 21/04 (2006.01); B60H 1/26 (2006.01); G01N 33/53 (2006.01); G01N 33/68 (2006.01); C12N 15/115 (2010.01); B60J 7/16 (2006.01); F04D 25/06 (2006.01); F04D 25/14 (2006.01);
U.S. Cl.
CPC ...
B60H 1/262 (2013.01); B60J 7/1642 (2013.01); C12N 15/115 (2013.01); F04D 25/0673 (2013.01); F04D 25/14 (2013.01); G01N 33/5308 (2013.01); G01N 33/68 (2013.01); C12N 2310/16 (2013.01);
Abstract

This application provides a method of using aptamers to determine the presence of HCP's in a recombinant protein preparation, and provides methods of preparing a plurality of aptamers for use in the method of detecting a plurality of HCP's in a recombinant protein preparation. In accordance with the description, a method of determining the presence or absence of a plurality of HCP's in a recombinant protein preparation comprises: providing a recombinant protein preparation; providing a final pool of aptamers; combining the recombinant protein preparation with the final pool of aptamers; and determining the presence or absence of a plurality of HCP's.


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