The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 18, 2021

Filed:

Mar. 13, 2017
Applicant:

The Johns Hopkins University, Baltimore, MD (US);

Inventors:

Kunal S. Parikh, Reynoldsburg, OH (US);

Himat Patel, Baltimore, MD (US);

Justin Hanes, Baltimore, MD (US);

Assignee:

THE JOHNS HOPKINS UNIVERSITY, Baltimore, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
D02G 1/02 (2006.01); D01D 7/00 (2006.01); A61L 17/00 (2006.01); A61L 17/10 (2006.01); A61L 17/12 (2006.01); D01D 5/00 (2006.01); D01F 1/10 (2006.01); D01H 7/02 (2006.01); A61L 31/06 (2006.01); A61L 31/14 (2006.01); A61B 17/06 (2006.01); A61K 31/5383 (2006.01); D04C 1/06 (2006.01);
U.S. Cl.
CPC ...
A61L 17/005 (2013.01); A61B 17/06166 (2013.01); A61K 31/5383 (2013.01); A61L 17/105 (2013.01); A61L 17/12 (2013.01); A61L 31/06 (2013.01); A61L 31/148 (2013.01); D01D 5/003 (2013.01); D01D 5/0007 (2013.01); D01D 5/0015 (2013.01); D01D 5/0023 (2013.01); D01D 5/0038 (2013.01); D01D 5/0046 (2013.01); D01D 5/0076 (2013.01); D01D 5/0084 (2013.01); D01F 1/10 (2013.01); D01F 1/103 (2013.01); D01H 7/02 (2013.01); D04C 1/06 (2013.01); A61L 2300/216 (2013.01); A61L 2300/402 (2013.01); A61L 2300/41 (2013.01); A61L 2300/416 (2013.01); A61L 2400/12 (2013.01); D10B 2331/04 (2013.01); D10B 2331/041 (2013.01); D10B 2401/12 (2013.01); D10B 2509/04 (2013.01); D10B 2509/06 (2013.01);
Abstract

A system for forming twisted or aligned electrospun fibers has been developed. The collector for the electrospun fibers is capable of rotation. In some instances, fibers are formed between two collectors, at least one of which rotates to twist the fibers into a multifilament bundle with increased strength. In a second embodiment, a cylindrical collector rotates, and charged polymer jet uniformly coats the surface of the collector. When a drum collector rotates at a high speed, electrospun fibers align and form an array. Optionally, different active agents can be included in the electrospinning solutions to form fiber constructs with different strengths and controlled release profiles, providing a reproducible method to generate complexed structures based on electrospun fibers and controlled drug delivery profiles.


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