The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 18, 2021

Filed:

Nov. 03, 2011
Applicants:

Jeffrey M. Gross, Carlsbad, CA (US);

Lev Drubetsky, Coquitlam, CA;

Alexander Naimagon, Richmond, CA;

Rui Avelar, Goleta, CA (US);

William L. D'agostino, Hamden, CT (US);

Kevin Don Nelson, Richardson, TX (US);

Brent B. Crow, Grand Prairie, TX (US);

Nickolas B. Griffin, Allen, TX (US);

Inventors:

Jeffrey M. Gross, Carlsbad, CA (US);

Lev Drubetsky, Coquitlam, CA;

Alexander Naimagon, Richmond, CA;

Rui Avelar, Goleta, CA (US);

William L. D'Agostino, Hamden, CT (US);

Kevin Don Nelson, Richardson, TX (US);

Brent B. Crow, Grand Prairie, TX (US);

Nickolas B. Griffin, Allen, TX (US);

Assignees:

Ethicon, Inc., Somerville, NJ (US);

Ethicon, LLC, Guaynabo, PR (US);

Tissuegen, Inc., Dallas, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 17/06 (2006.01); A61B 17/04 (2006.01); A61L 17/00 (2006.01); A61B 17/00 (2006.01);
U.S. Cl.
CPC ...
A61L 17/005 (2013.01); A61B 17/0401 (2013.01); A61B 2017/00526 (2013.01); A61B 2017/00893 (2013.01); A61B 2017/0608 (2013.01); A61B 2017/06057 (2013.01); A61B 2017/06176 (2013.01); A61L 2300/414 (2013.01); A61L 2300/602 (2013.01); A61L 2430/32 (2013.01);
Abstract

A drug-eluting self-retaining suture comprises a filament, a plurality of retainers, and a drug impregnated in or coated on the filament. The shape and distribution of retainers modifies the in vivo release kinetics of the drug. The drug release kinetics may be modified uniformly or region by region. The self-retaining suture may for example be used for reattaching severed nerves and release nerve growth factor or other regeneration accelerating agents into the region of the nerve injury.


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