The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 18, 2021
Filed:
Nov. 04, 2019
Applicant:
Sanofi, Paris, FR;
Inventors:
Assignee:
SANOFI, Paris, FR;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/336 (2006.01); C07D 303/02 (2006.01); A61K 47/65 (2017.01); C07D 405/14 (2006.01); A61K 47/68 (2017.01); C07D 405/06 (2006.01); C07K 11/00 (2006.01); A61K 47/64 (2017.01); A61P 35/00 (2006.01); A61K 38/15 (2006.01); A61K 47/10 (2017.01); A61K 47/22 (2006.01);
U.S. Cl.
CPC ...
A61K 47/65 (2017.08); A61K 38/15 (2013.01); A61K 47/10 (2013.01); A61K 47/22 (2013.01); A61K 47/64 (2017.08); A61K 47/6829 (2017.08); A61K 47/6889 (2017.08); A61P 35/00 (2018.01); C07D 405/06 (2013.01); C07D 405/14 (2013.01); C07K 11/00 (2013.01);
Abstract
The present disclosure relates to compounds of formula (V): wherein Ab represents an antibody. The disclosure also relates to cryptophycin payloads, as well as to cryptophycin conjugates, to compositions containing them and to their therapeutic use, especially as anticancer agents. The disclosure also relates to the process for preparing these conjugates.