The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 18, 2021
Filed:
Nov. 13, 2017
Applicant:
Tokyo University of Science Foundation, Tokyo, JP;
Inventors:
Etsuko Miyamoto, Tokyo, JP;
Masaaki Ozawa, Tokyo, JP;
Assignee:
Tokyo University of Science Foundation, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/54 (2017.01); A61P 7/04 (2006.01); A61P 35/00 (2006.01); A61K 31/167 (2006.01);
U.S. Cl.
CPC ...
A61K 47/54 (2017.08); A61K 31/167 (2013.01); A61P 7/04 (2018.01); A61P 35/00 (2018.01);
Abstract
A p53 degradation inducing molecule which can induce degradation of p53 proteins or p53 composites, and a pharmaceutical composition containing said p53 degradation inducing molecule are provided. This p53 degradation inducing molecule is a conjugate of a p53 affinity molecule which has affinity for p53 proteins or p53 composites, and a proteolysis induction tag which has affinity for protease and which does not inhibit proteolysis of proteins by protease.