The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 18, 2021

Filed:

Aug. 06, 2018
Applicant:

International Stem Cell Corporation, Carlsbad, CA (US);

Inventors:

Russell A. Kern, Carlsbad, CA (US);

Rodolfo Gonzalez, Carlsbad, CA (US);

Ibon Garitaonandia, Carlsbad, CA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/0797 (2010.01); A61K 35/545 (2015.01); A61K 35/30 (2015.01); C12N 5/074 (2010.01);
U.S. Cl.
CPC ...
A61K 35/545 (2013.01); A61K 35/30 (2013.01); C12N 5/0623 (2013.01); C12N 5/0696 (2013.01); C12N 2501/155 (2013.01); C12N 2501/727 (2013.01); C12N 2506/02 (2013.01); C12N 2506/45 (2013.01);
Abstract

The present invention is based in part methods for treating neurodegenerative diseases and disorders. Specifically, the present invention disclose methods for treating neurodegenerative disorders suing neural stem cells (NSCs) and/or pluripotent stem cell (PSC) derived neurons or neuron precursor cells. The present invention also discloses methods to induce endogenous dopaminergic neurons to release dopamine and increase the levels of dopamine in a subject.


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