The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 18, 2021

Filed:

Jul. 31, 2018
Applicant:

Summit Innovation Labs, Llc, Norwood, OH (US);

Inventors:

Haile Mehansho, Hamilton, OH (US);

Satyanarayana Majeti, Liberty Township, OH (US);

Ghebre Egziabher Tzeghai, Wyoming, OH (US);

Assignee:

Summit Innovation Labs, LLC, Norwood, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/353 (2006.01); A61K 31/05 (2006.01); A61K 31/047 (2006.01); A61K 31/7048 (2006.01); A61K 47/22 (2006.01); A61K 47/12 (2006.01); A61K 9/00 (2006.01); A61P 19/02 (2006.01); A61K 31/12 (2006.01); A61K 33/30 (2006.01); A61K 33/08 (2006.01); A61K 33/10 (2006.01); A61K 33/14 (2006.01); A61K 33/26 (2006.01);
U.S. Cl.
CPC ...
A61K 31/353 (2013.01); A61K 9/0053 (2013.01); A61K 31/047 (2013.01); A61K 31/05 (2013.01); A61K 31/12 (2013.01); A61K 31/7048 (2013.01); A61K 47/12 (2013.01); A61K 47/22 (2013.01); A61P 19/02 (2018.01); A61K 33/08 (2013.01); A61K 33/10 (2013.01); A61K 33/14 (2013.01); A61K 33/26 (2013.01); A61K 33/30 (2013.01); A61K 2300/00 (2013.01);
Abstract

The invention encompasses compositions and methods for effectively treating and/or preventing the development and/or progression of osteoarthritis and rheumatoid arthritis and for promoting overall joint health. This is accomplished by totally addressing the key multiple biochemical processes and mechanisms that lead to such disorders. The invention includes compositions comprising a combination of natural agents that safely and effectively suppress, regulate or interfere with the various biochemical processes and mechanisms that increase the risk for or lead to the development and/or progression of OA and RA. The present compositions are holistically formulated to be effective in preventing/arresting loss of and/or damage to the articular cartilage (AC) by suppressing (a) extracellular matrix (ECM) degradation, (b) chondrocyte apoptosis, and (c) inflammation of synovium through modulation of mechanisms that involve transcription factors, growth factors, kinases, antiapoptotic/apoptotic factors and deacetylases. The active agents used herein are natural materials, in particular phytonutrients (or phytochemicals), minerals and/or vitamins.


Find Patent Forward Citations

Loading…