The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 11, 2021

Filed:

Jul. 29, 2016
Applicant:

University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);

Inventors:

Joyeeta Dutta-Moscato, Pittsburgh, PA (US);

Liang-I Kang, Pittsburgh, PA (US);

Qi Mi, Pittsburgh, PA (US);

Kari Nejak-Bowen, White Oak, PA (US);

Yoram Vodovotz, Sewickley, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G16B 50/00 (2019.01); G16H 50/50 (2018.01);
U.S. Cl.
CPC ...
G16B 50/00 (2019.02); G16H 50/50 (2018.01);
Abstract

Provided herein are in silico methods of modeling hepatic inflammation, fibrosis/cirrhosis, and cancer. The models are computer-implemented agent-based models and are useful in determining patient prognoses in hepatic conditions, including viral infections, damage, inflammation, and cancer. The modeling system also is useful in modeling the effects of active agents on normal hepatic tissue or hepatic tissue perturbed by inflammation, infection, damage, fibrosis/cirrhosis, and cancer.


Find Patent Forward Citations

Loading…