The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 11, 2021
Filed:
Nov. 10, 2017
University of South Florida, Tampa, FL (US);
Stereology Resource Center, Inc., St. Petersburg, FL (US);
Peter Randolph Mouton, St. Petersburg, FL (US);
Hady Ahmady Phoulady, Portland, ME (US);
Dmitry Goldgof, Lutz, FL (US);
Lawrence O. Hall, Tampa, FL (US);
UNIVERSITY OF SOUTH FLORIDA, Tampa, FL (US);
STEREOLOGY RESOURCE CENTER, INC., St. Petersburg, FL (US);
Abstract
Systems and methods for automated stereology are provided. A method can include providing an imager for capturing a Z-stack of images of a three-dimensional (3D) object; constructing extended depth of field (EDF) images from the Z-stack of images; performing a segmentation method on the EDF images including estimating a Gaussian Mixture Model (GMM), performing morphological operations, performing watershed segmentation, constructing Voronoi diagrams and performing boundary smoothing; and determining one or more stereology parameters such as number of cells in a region.