The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 11, 2021
Filed:
Mar. 13, 2018
Applicant:
Spring Bioscience Corporation, Pleasanton, CA (US);
Inventors:
Yifei Zhu, San Jose, CA (US);
Zhiming Liao, Livermore, CA (US);
Fernando Jose Rebelo do Couto, Pleasanton, CA (US);
Assignee:
Ventana Medical Systems, Inc., Tucson, AZ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); C07K 16/30 (2006.01); C07K 16/28 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/574 (2013.01); C07K 16/28 (2013.01); C07K 16/30 (2013.01); G01N 33/57411 (2013.01); G01N 33/57423 (2013.01); G01N 33/6893 (2013.01); C07K 2317/20 (2013.01); G01N 2333/705 (2013.01);
Abstract
The present application discloses anti-GPNMB antibodies and methods of using the same. The antibodies are selected to bind to an epitope located in a C-terminal fragment of the protein and are selected for specificity in immunohistochemical assays. The antibodies are useful in, for example, immunohistochemical methods of detecting GPNMB-positive cells in tumors.