The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 11, 2021

Filed:

Jun. 12, 2018
Applicant:

Personal Genomics Taiwan, Inc., Hsinchu County, TW;

Inventors:

Chung-Fan Chiou, Hsinchu County, TW;

Chao-Chi Pan, Hsinchu, TW;

Ching-Wei Tsai, Taoyuan, TW;

Bor-Huah Chen, Taichung, TW;

Jian-Hao Ciou, Changhua County, TW;

Assignee:

Personal Genomics Taiwan, Inc., Hsinchu County, TW;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/6869 (2018.01); C12Q 1/6876 (2018.01); C12Q 1/6874 (2018.01); C07H 21/04 (2006.01); B01L 3/00 (2006.01); B01J 19/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6869 (2013.01); B01J 19/0046 (2013.01); B01L 3/5082 (2013.01); B01L 3/5085 (2013.01); B01L 3/50857 (2013.01); C07H 21/04 (2013.01); C12Q 1/6874 (2013.01); C12Q 1/6876 (2013.01); B01J 2219/00317 (2013.01); B01J 2219/00511 (2013.01); B01J 2219/00722 (2013.01); B01L 2300/0896 (2013.01); B01L 2300/16 (2013.01); C12Q 2521/101 (2013.01); C12Q 2521/525 (2013.01); C12Q 2525/186 (2013.01); C12Q 2531/125 (2013.01); C12Q 2563/107 (2013.01); C12Q 2563/159 (2013.01);
Abstract

An apparatus suitable for single molecule sequencing. The apparatus includes at least one nanowell, a plurality of nucleic acid immobilization moieties, and a plurality of types of nucleic acid fragments. The nanowell has an observation zone. The nucleic acid immobilization moieties are disposed in or proximate to the observation zone. The nucleic acid fragments are immobilized to the nucleic acid immobilization moieties, respectively. At least one polymerase is disposed in the observation zone. A method of sequencing nucleic acid molecules using the above-mentioned apparatus is provided.


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