The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 11, 2021
Filed:
Oct. 14, 2016
Applicant:
Wake Forest University Health Sciences, Winston-Salem, NC (US);
Inventors:
Sean V. Murphy, Winston-Salem, NC (US);
Anthony Atala, Winston-Salem, NC (US);
Assignee:
Wake Forest University Health Sciences, Winston-Salem, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/071 (2010.01); C12M 3/00 (2006.01); C12M 3/06 (2006.01); C12M 1/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0697 (2013.01); C12M 21/08 (2013.01); C12M 23/16 (2013.01); C12M 23/22 (2013.01); C12N 5/0688 (2013.01); C12N 2502/27 (2013.01); C12N 2502/28 (2013.01); C12N 2533/54 (2013.01); C12N 2533/90 (2013.01);
Abstract
Provided herein are artificial lung organoids. The artificial lung organoids may include an epithelial cell layer comprising mammalian lung epithelial cells, a stromal cell layer comprising mammalian lung fibroblast cells and an endothelial cell layer comprising mammalian endothelial cells. The artificial lung organoids may optionally include a porous membrane between said epithelial cell layer and said stromal cell layer and/or between said stromal cell layer and said endothelial lung cell layer.