The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 11, 2021

Filed:

Dec. 20, 2017
Applicant:

Adel Inc., Seoul, KR;

Inventors:

Seung-Yong Yoon, Seoul, KR;

Na-Young Kim, Seoul, KR;

Dong-Hou Kim, Yeongwol-gun, KR;

Assignee:

ADEL INC., Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); A61P 25/28 (2006.01); A61K 39/00 (2006.01); C07K 16/18 (2006.01); G01N 33/68 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4711 (2013.01); A61K 39/0007 (2013.01); A61P 25/28 (2018.01); C07K 16/18 (2013.01); G01N 33/6896 (2013.01); A61K 38/00 (2013.01); C07K 2317/76 (2013.01); G01N 2800/2821 (2013.01); G01N 2800/2835 (2013.01);
Abstract

The present invention relates to a mutated tau protein fragment and a use thereof. The mutated tau protein fragment of the present invention consists of 12 amino acids and thus can easily be prepared. In addition, when the mutated tau protein fragment is injected into an individual as an antigen, a neutralizing antibody against the mutated tau protein is generated. Moreover, the mutated tau protein fragment reduces the aggregation of abnormal tau proteins. Accordingly, the mutated tau protein fragment of the present invention can be effectively used for the prevention or treatment of degenerative neurological diseases.


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