The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 11, 2021
Filed:
Sep. 19, 2019
Applicant:
Forma Therapeutics, Inc., Watertown, MA (US);
Inventors:
David R. Lancia, Jr., Boston, MA (US);
Gary Gustafson, Ridgefield, CT (US);
Neal Green, Newton, MA (US);
Lorna Mitchell, West Beach, AU;
Anna Ericsson, Shrewsbury, MA (US);
David Richard, Littleton, MA (US);
Assignee:
Forma Therapeutics, Inc., Watertown, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61K 31/4439 (2006.01); C07D 487/04 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 9/0053 (2013.01);
Abstract
The disclosure provides chemical compounds useful as activators of PKR. PKR activating compounds are useful in the treatment of disease and disorders associated with modulation of PKR and/or PKM2, such as pyruvate kinase deficiency (PKD).