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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11001573 B1

PDFFull Text
Date of Patent:
May. 11, 2021

Filed:

Oct. 15, 2019

Citric acid derivative

Applicants:

Adabio Co., Ltd., Gunma, JP;

Otsuka Pharmaceutical Factory, Inc., Tokushima, JP;

Inventors:

Katsuya Hiraishi, Gunma, JP;

Fumie Jimma, Gunma, JP;

Hiroyuki Soma, Gunma, JP;

Taro Adachi, Gunma, JP;

Masakazu Adachi, Gunma, JP;

Ippei Yamaoka, Tokushima, JP;

Tomohiro Kagawa, Tokushima, JP;

Assignees:

ADABIO CO., LTD., Gunma, JP;

OTSUKA PHARMACEUTICAL FACTORY, INC., Tokushima, JP;

Attorney:

Greenblum & Bernstein, P.L.C.

Primary Examiner:

Kamal A Saeed

Int. Cl.
CPC ...
C07D 405/04 (2006.01); A61K 31/341 (2006.01); A23L 33/105 (2016.01); C07C 231/02 (2006.01); C07C 235/12 (2006.01); C07D 207/416 (2006.01); A61K 31/194 (2006.01); C07C 233/12 (2006.01); C07D 207/12 (2006.01); C07D 307/20 (2006.01); A61K 31/197 (2006.01); A61K 31/4015 (2006.01); A61K 31/4025 (2006.01);
U.S. Cl.
CPC ...
C07D 405/04 (2013.01); A23L 33/105 (2016.08); A61K 31/194 (2013.01); A61K 31/197 (2013.01); A61K 31/341 (2013.01); A61K 31/4015 (2013.01); A61K 31/4025 (2013.01); C07C 231/02 (2013.01); C07C 233/12 (2013.01); C07C 235/12 (2013.01); C07D 207/12 (2013.01); C07D 207/416 (2013.01); C07D 307/20 (2013.01); A23V 2002/00 (2013.01);
Abstract

Compounds (citric acid derivatives) represented by formulas (1) and (2) below are novel compounds having an inhibitory effect against liver disorder and can be used as liver disorder inhibitors and food additives (wherein Rrepresents a C1 to C3 alkyl group optionally having a carboxyl group or a hydroxyl group, and Rrepresents a hydrogen atom, or Rand Roptionally form a cyclic structure together to represent a C2 to C3 alkylene chain).

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