The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 11, 2021
Filed:
Sep. 13, 2017
Applicant:
Arbutus Biopharma Corporation, Burnaby, CA;
Inventors:
Andrew G. Cole, Cranbury, NJ (US);
Steven Kultgen, Hamilton, NJ (US);
Assignee:
Arbutus Biopharma Corporation, Burnaby, CA;
Primary Examiner:
Int. Cl.
CPC ...
C07D 311/58 (2006.01); C07D 335/06 (2006.01); C07D 405/12 (2006.01); C07D 407/12 (2006.01); C07D 409/12 (2006.01); C07D 417/12 (2006.01); C07D 405/04 (2006.01); C07C 201/00 (2006.01); C07D 401/12 (2006.01); C07D 311/68 (2006.01); C07D 215/42 (2006.01); C07D 213/30 (2006.01); C07D 311/22 (2006.01); C07C 275/26 (2006.01); C07C 271/24 (2006.01); A61P 31/20 (2006.01); C07D 311/20 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
C07D 311/58 (2013.01); A61P 31/20 (2018.01); C07C 201/00 (2013.01); C07C 271/24 (2013.01); C07C 275/26 (2013.01); C07D 213/30 (2013.01); C07D 215/42 (2013.01); C07D 311/20 (2013.01); C07D 311/22 (2013.01); C07D 311/68 (2013.01); C07D 335/06 (2013.01); C07D 401/12 (2013.01); C07D 405/04 (2013.01); C07D 405/12 (2013.01); C07D 407/12 (2013.01); C07D 409/12 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/12 (2013.01); C07C 2602/10 (2017.05);
Abstract
The present invention includes novel substituted bicyclic (such as 4-substituted-chromane-8-carboxamide compounds), and compositions comprising the same, that can be used to treat or prevent hepatitis B virus (HBV) infections in a patient. In certain embodiments, the compounds and compositions of the invention are capsid inhibitors.