The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 11, 2021

Filed:

Oct. 18, 2017
Applicant:

Korea Institute of Science and Technology, Seoul, KR;

Inventors:

Young Mee Jung, Seoul, KR;

Soo Hyun Kim, Seoul, KR;

Su Hee Kim, Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B29C 64/314 (2017.01); B29C 64/106 (2017.01); B33Y 80/00 (2015.01); A61L 27/14 (2006.01); A61L 27/58 (2006.01); A61L 31/14 (2006.01); C08G 63/08 (2006.01); C08K 5/00 (2006.01); C08K 3/08 (2006.01); B29C 64/209 (2017.01); B33Y 10/00 (2015.01); B33Y 70/00 (2020.01); C08K 5/1545 (2006.01); A61L 27/50 (2006.01); A61L 27/18 (2006.01);
U.S. Cl.
CPC ...
B29C 64/106 (2017.08); A61L 27/14 (2013.01); A61L 27/18 (2013.01); A61L 27/505 (2013.01); A61L 27/58 (2013.01); A61L 31/143 (2013.01); B29C 64/209 (2017.08); B29C 64/314 (2017.08); B33Y 10/00 (2014.12); B33Y 70/00 (2014.12); B33Y 80/00 (2014.12); C08G 63/08 (2013.01); C08K 3/08 (2013.01); C08K 5/005 (2013.01); C08K 5/1545 (2013.01); C08K 2003/0893 (2013.01);
Abstract

A method for preparing a highly elastic biodegradable three-dimensional structure includes (a) mixing poly(lactide-co-ε-caprolactone) (PLCL) with at least one biocompatible heat stabilizer that is biocompatible with the PLCL, that is a heat stabilizer for the PLCL, and that is selected from the group consisting of α-tocopherol, barium-zinc, calcium-zinc, vitamin B, and combinations thereof to provide a solvent-free mixture; and (b) carrying out three-dimensional printing with the solvent-free mixture by heating the mixture at 150-250° C. for 5-20 minutes to provide a heated mixture; and ejecting the heated mixture through a nozzle. The three-dimensional structure maintains mechanical properties even after three-dimensional printing, by adding a biocompatible heat stabilizer to poly(L-lactide-co-ε-caprolactone). The three-dimensional structure is useful as a scaffold for tissue engineering.


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