The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 11, 2021
Filed:
Jun. 05, 2019
Applicant:
Industry-university Cooperation Foundation Hanyang University, Seoul, KR;
Inventors:
Chae Ok Yun, Seoul, KR;
Joung-Woo Choi, Seoul, KR;
Assignee:
GENEMEDICINE CO., LTD., , KR;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 41/00 (2020.01); C12N 7/00 (2006.01); C12N 15/86 (2006.01); A61K 9/51 (2006.01); A61K 47/60 (2017.01); A61K 47/64 (2017.01); A61K 47/69 (2017.01); A61K 35/761 (2015.01);
U.S. Cl.
CPC ...
A61K 41/00 (2013.01); A61K 9/5146 (2013.01); A61K 9/5169 (2013.01); A61K 41/0052 (2013.01); A61K 47/60 (2017.08); A61K 47/645 (2017.08); A61K 47/6923 (2017.08); A61K 47/6941 (2017.08); C12N 7/00 (2013.01); C12N 15/86 (2013.01); A61K 35/761 (2013.01); C12N 2710/10332 (2013.01); C12N 2710/10343 (2013.01);
Abstract
The present disclosure relates to a composition for transduction of a virus in a cell by using a crosslinked product of PEGylated magnetic nanoparticles and catechol grafted poly-L-lysine by application of an external magnetic field. When the composition is used, a virus may be delivered into cells more rapidly and efficiently than in intracellular uptake of a virus by CAR-mediated endocytosis.