The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 11, 2021

Filed:

Feb. 28, 2019
Applicants:

The University of Tokyo, Tokyo, JP;

Tohoku University, Miyagi, JP;

Inventors:

Kotaro Yoshimura, Tokyo, JP;

Kahori Kinoshita, Tokyo, JP;

Mari Dezawa, Miyagi, JP;

Assignees:

The University of Tokyo, Tokyo, JP;

Tohoku University, Miyagi, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/28 (2015.01); A61K 35/12 (2015.01); A61K 35/545 (2015.01); A61P 17/02 (2006.01); A61P 3/10 (2006.01);
U.S. Cl.
CPC ...
A61K 35/28 (2013.01); A61K 35/12 (2013.01); A61K 35/545 (2013.01); A61P 3/10 (2018.01); A61P 17/02 (2018.01);
Abstract

The purpose of the present invention is to provide a novel medicinal use in regeneration medicine, said medicinal use comprising using pluripotent stem cells (Muse cells). Provided is a cell preparation for treating skin ulcer, said cell preparation comprising SSEA-3 positive pluripotent stem cells isolated from a mesenchymal tissue of a living organism or cultured mesenchymal cells. The cell preparation according to the present invention is based on such mechanism of skin tissue regeneration that, when the Muse cells are administered to a skin ulcer site of a subject suffering from the aforesaid disease, the Muse cells differentiate into skin-constituting cells.


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