The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 11, 2021
Filed:
May. 03, 2018
Athersys, Inc., Cleveland, OH (US);
Oregon Health & Science University, Portland, OR (US);
Robert Deans, Riverside, CA (US);
Richard Maziarz, Portland, OR (US);
Magdalena Kovacsovics, Portland, OR (US);
Philip Streeter, Oregon City, OR (US);
Wouter Van't Hof, Shaker Heights, OH (US);
ATHERSYS, INC., Cleveland, OH (US);
OREGON HEALTH & SCIENCE UNIVERISTY, Portland, OR (US);
Abstract
Isolated cells are described that are not embryonic stem cells, not embryonic germ cells, and not germ cells. The cells can differentiate into at least one cell type of each of at least two of the endodermal, ectodermal, and mesodermal lineages. The cells do not provoke a harmful immune response. The cells can modulate immune responses. As an example, the cells can suppress an immune response in a host engendered by allogeneic cells, tissues, and organs. Methods are described for using the cells, by themselves or adjunctively, to treat subjects. For instance, the cells can be used adjunctively for immunosuppression in transplant therapy. Methods for obtaining the cells and compositions for using them also are described.