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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11000524 B1

PDFFull Text
Date of Patent:
May. 11, 2021

Filed:

Dec. 01, 2017

Tyrosine kinase inhibition as a treatment for epilepsy

Applicant:

Iowa State University Research Foundation, Inc., Ames, IA (US);

Inventors:

Thimmasettappa Thippeswamy, Ames, IA (US);

Anumantha G. Kanthasamy, Ames, IA (US);

Assignee:

Iowa State University Research Foundation, Inc., Ames, IA (US);

Attorney:

McKee, Voorhees & Sease, PLC

Primary Examiner:

Anna Pagonakis

Int. Cl.
CPC ...
A61K 31/517 (2006.01); A61K 31/18 (2006.01); A61K 31/19 (2006.01); A61K 31/325 (2006.01); A61K 31/4015 (2006.01); A61K 31/4166 (2006.01); A61K 31/515 (2006.01); A61K 31/5513 (2006.01); A61K 31/7024 (2006.01); A61K 9/00 (2006.01); A61K 45/06 (2006.01); A61P 25/08 (2006.01); A61K 31/53 (2006.01);
U.S. Cl.
CPC ...
A61K 31/517 (2013.01); A61K 9/0053 (2013.01); A61K 31/18 (2013.01); A61K 31/19 (2013.01); A61K 31/325 (2013.01); A61K 31/4015 (2013.01); A61K 31/4166 (2013.01); A61K 31/515 (2013.01); A61K 31/53 (2013.01); A61K 31/5513 (2013.01); A61K 31/7024 (2013.01); A61K 45/06 (2013.01); A61P 25/08 (2018.01);
Abstract

The present invention describes novel pharmaceutical compositions and methods for treatment of diseases, disorders, or conditions characterized by recurrent seizures, particularly, epilepsy. According to the invention, compounds which inhibit the activity or expression of non-receptor Fyn tyrosine kinase can prevent activation epileptic pathophysiology and provide protection from and treatment of epilepsy. Particularly preferred is the class of small molecule Fyn kinase inhibitors such as sacaratinib and its prodrugs, derivatives, analogs and the like.

Find Patent Forward Citations

Thippeswamy, Thimmasettappa. (2021). Tyrosine kinase inhibition as a treatment for epilepsy (U.S. Patent No. 11000524). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11000524

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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