The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 11, 2021

Filed:

Mar. 12, 2020
Applicants:

Lupin Inc., Baltimore, MD (US);

Charles Williams Flexner;

Inventors:

Helen S. Pentikis, Timonium, MD (US);

David Palling, Glen Ridge, NJ (US);

Carol J. Braun, Ellicott City, MD (US);

Richard Holl, Somerset, NJ (US);

Assignee:

LUPIN INC., Baltimore, MD (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4164 (2006.01); A61K 45/06 (2006.01); C07D 233/94 (2006.01); A61K 31/565 (2006.01); A61K 31/567 (2006.01); A61K 9/00 (2006.01); A61K 9/16 (2006.01); A61K 9/50 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4164 (2013.01); A61K 9/0053 (2013.01); A61K 9/1676 (2013.01); A61K 9/5078 (2013.01); A61K 31/565 (2013.01); A61K 31/567 (2013.01); A61K 45/06 (2013.01); C07D 233/94 (2013.01);
Abstract

Method of treating bacterial vaginosis in a subject in need thereof involving administering to the subject a therapeutically effective amount of secnidazole in a microgranule formulation, wherein the microgranule formulation comprises a plurality of microgranules having a volume-weighted particle size distribution within a microgranule population, wherein the volume-weighted particle size distribution as measured from a representative sample of the microgranule population comprises (a) at least 10% of the microgranule population having a volume-weighted particle size about no less than 470 micrometers; or (b) 50% of the microgranule population having a volume-weighted particle size between about no less than 640 micrometers and about no more than 810 micrometers; or (c) 90% of the microgranule population having a volume-weighted particle size about no more than 1170 micrometers; or (d) a combination thereof, which can include some or all of (a) through (c) above.


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