logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11000467 B1

PDFFull Text
Date of Patent:
May. 11, 2021

Filed:

Oct. 14, 2016

In situ cross-linkable polysaccharide compositions and uses thereof

Applicant:

Merz Pharma Gmbh & Co. Kgaa, Frankfurt am Main, DE;

Inventor:

Andreas Krause, Frankfurt am Main, DE;

Assignee:

Merz Pharma GmbH & Co. KGaA, Frankfurt Am Main, DE;

Attorney:

McBee Moore & Vanik IP, LLC

Primary Examiner:

Nicole P Babson

Int. Cl.
CPC ...
A61K 8/73 (2006.01); A61L 27/20 (2006.01); A61K 8/04 (2006.01); A61K 31/738 (2006.01); A61L 27/52 (2006.01); A61Q 19/08 (2006.01); C08L 5/08 (2006.01); A61K 47/36 (2006.01); A61K 9/00 (2006.01); C08B 37/08 (2006.01); A61K 31/728 (2006.01);
U.S. Cl.
CPC ...
A61K 8/735 (2013.01); A61K 8/042 (2013.01); A61K 9/0024 (2013.01); A61K 31/728 (2013.01); A61K 31/738 (2013.01); A61K 47/36 (2013.01); A61L 27/20 (2013.01); A61L 27/52 (2013.01); A61Q 19/08 (2013.01); C08B 37/0072 (2013.01); C08L 5/08 (2013.01); A61K 2800/594 (2013.01); A61K 2800/87 (2013.01); A61K 2800/88 (2013.01); A61K 2800/882 (2013.01); A61K 2800/91 (2013.01); A61K 2800/95 (2013.01); A61L 2400/06 (2013.01);
Abstract

The present invention relates to a sterile in situ cross-linkable polysaccharide compositions for augmenting, filling or replacing soft tissues in various cosmetic and therapeutic applications. The composition comprises a first polysaccharide derivative functionalized with a nucleophilic group and a second polysaccharide derivative functionalized with an electrophilic group. Said nucleophilic and electrophilic functional groups spontaneously form in situ covalent linkages following co-injection in the body of a patient, resulting in the formation of a cross-linked hydrogel at the site of co-injection.

Find Patent Forward Citations

Loading…