The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 04, 2021

Filed:

Oct. 10, 2019
Applicants:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

The Governing Council of the University of Toronto, Toronto, CA;

Inventors:

Ursula-Henrike Wienhues-Thelen, Krailling, DE;

Georg Hess, Mainz, DE;

Hendrik Huedig, Penzberg, DE;

Herbert von der Eltz, Weilheim, DE;

Andrew Emili, Toronto, CA;

Anthony Gramolini, Toronto, CA;

Peter Liu, Toronto, CA;

David MacLennan, Toronto, CA;

Vincent Fong, Auincourt, CA;

Ruth Isserlin, Thornhill, CA;

Thomas Kislinger, Toronto, CA;

Dirk Block, Bichl, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6893 (2013.01); G01N 2333/47 (2013.01); G01N 2333/4727 (2013.01); G01N 2333/4737 (2013.01); G01N 2333/4745 (2013.01); G01N 2333/5412 (2013.01); G01N 2333/58 (2013.01); G01N 2800/325 (2013.01); G01N 2800/56 (2013.01);
Abstract

Disclosed is a method for assessing heart failure in vitro including the steps of measuring in a sample the concentration of the marker IGFBP-7, of optionally measuring in the sample the concentration of one or more other marker(s) of heart failure, and of assessing heart failure by comparing the concentration determined in for IGFBP-7 and the concentration(s) determined for the optionally one or more other marker to the concentration of this marker or these markers as established in a reference population. Also disclosed are the use of IGFBP-7 as a marker protein in the assessment of heart failure, a marker combination comprising IGFBP-7 and a kit for measuring IGFBP-7.


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