The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 04, 2021

Filed:

Mar. 22, 2017
Applicant:

Mogene Green Chemicals Llc, St. Louis, MO (US);

Inventors:

Jana Stockel, St. Louis, MO (US);

Abhay Kumar Singh, Chesterfield, MO (US);

Himadri Pakrasi, St. Louis, MO (US);

Ganesh Murthy Kishore, Creve Coeur, MO (US);

Assignee:

MOgene Green Chemicals LLC, St. Louis, MO (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/10 (2006.01); C12N 9/14 (2006.01); C12P 17/18 (2006.01); C12N 15/52 (2006.01);
U.S. Cl.
CPC ...
C12P 17/182 (2013.01); C12N 9/1007 (2013.01); C12N 9/1085 (2013.01); C12N 9/14 (2013.01); C12N 15/52 (2013.01); C12Y 201/0116 (2013.01); C12Y 201/01158 (2013.01); C12Y 201/01159 (2013.01); C12Y 205/01006 (2013.01); C12Y 303/01001 (2013.01);
Abstract

Provided herein are microorganisms that include one or more heterologous nucleic acid selected from the group of a sequence encoding a 7-methylxanthosine synthase, a sequence encoding a theobromine synthase; and a sequence encoding a caffeine synthase, where the microorganism is capable of producing one or more purine alkaloid in a culture medium, when the microorganism is cultured under conditions sufficient to produce the one or more purine alkaloid. Also provided compositions and kits that include at least one of these microorganisms, and methods of producing one or more purine alkaloid that include culturing one of these microorganisms under conditions sufficient to produce the one or more purine alkaloid.


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