The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 04, 2021

Filed:

Sep. 30, 2019
Applicants:

United States Government As Represented BY the Department of Veterans Affairs, Washington, DC (US);

The University of Pittsburgh—of the Commonwealth of Higher Education, Pittsburgh, PA (US);

Xiamen University, Fujian, CN;

University of Exeter, Exeter, GB;

Inventors:

Dandan Sun, Pittsburgh, PA (US);

Xianming Deng, Fujian, CN;

Jinwei Zhang, Exeter, GB;

Mohammad Iqbal Hossain Bhuiyan, Pittsburgh, PA (US);

Bradley J. Molyneaux, Pittsburgh, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 255/44 (2006.01); A61P 25/28 (2006.01);
U.S. Cl.
CPC ...
C07C 255/44 (2013.01); A61P 25/28 (2018.01);
Abstract

The present disclosure is concerned with N-(5-chloro-4-((4-chlorophenyl)(cyano)methyl)-2-methylphenyl)benzamide compounds that are capable of inhibiting SPAK kinase function, methods of treating hypoxic brain injuries due to, for example, ischemic stroke. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.


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