The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10995054 B1

PDF
Full Text
Expired
Date of Patent:
May. 04, 2021

Filed:

Oct. 16, 2017
Applicant:

Agency for Science, Technology and Research, Singapore, SG;

Inventor:

Teck Hock Lee, Singapore, SG;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 69/72 (2006.01); A61K 49/10 (2006.01); C07B 59/00 (2006.01); C07C 67/48 (2006.01);
U.S. Cl.
CPC ...
C07C 69/72 (2013.01); A61K 49/10 (2013.01); C07B 59/001 (2013.01); C07C 67/48 (2013.01); C07B 2200/05 (2013.01);
Abstract

The present invention relates to hyperpolarized [3-C]acetoacetate. Provided are [3-C]acetoacetate and compositions comprising said [3-C]acetoacetate. Further provided are methods of preparing and using hyperpolarized [3-C]acetoacetate in the determination of the spatial and temporal distribution and metabolism of [3-C]acetoacetate and/or its metabolites in a cell or subject, preferably by magnetic resonance imaging (MRI), magnetic resonance spectroscopy (MRS), and/or magnetic resonance spectroscopic imaging (MRSI), whereby conditions, diseases, or disorders associated with the metabolism of acetoacetate and/or other ketone bodies can be diagnosed. The conditions, diseases, or disorders to be diagnosed preferably are cancer, diabetes, cardiovascular diseases, or neurodegenerative diseases.


Find Patent Forward Citations

Lee, Teck. (2021). Hyperpolarized [3-c]acetoacetate and methods of using the same (U.S. Patent No. 10995054). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10995054

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