The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 04, 2021

Filed:

Aug. 31, 2018
Applicant:

Cytonome/st, Llc, Bedford, MA (US);

Inventors:

Andrew Johnson, Randolph, MA (US);

John R. Gilbert, Brookline, MA (US);

Manish Deshpande, Canton, MA (US);

Hugh Lewis, Gravelotte, ZA;

Bernard Bunner, Watertown, MA (US);

Assignee:

CYTONOME/ST, LLC, Bedford, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); C12N 5/00 (2006.01); B07C 5/34 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502761 (2013.01); B01L 3/52 (2013.01); B07C 5/34 (2013.01); C12N 5/0081 (2013.01); B01L 2200/027 (2013.01); B01L 2200/028 (2013.01); B01L 2200/0636 (2013.01); B01L 2200/0652 (2013.01); B01L 2200/0689 (2013.01); B01L 2300/021 (2013.01); B01L 2300/0636 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0864 (2013.01); B01L 2400/04 (2013.01); B01L 2400/0439 (2013.01); B01L 2400/0442 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/0622 (2013.01);
Abstract

An improved actuator for use in a microfluidic particle sorting system utilizes a staggered packing scheme for a plurality of actuators used to selectively deflect a particle in an associated sorting channel from a stream of channels. An actuator block may be provided for housing a two-dimensional array of actuators, each configured to align with an actuation port in an associated sorting chip containing a plurality of sorting channels. The actuator block may include a built-in stressing means to pre-stress each actuator housed by the block. An actuator comprising a piezo-electric stack may employ contact-based electrical connection rather than soldered wires to improve packing density. The actuator may be an external actuator. That is, the external actuator is external to the substrate in which the sorting channels are formed.


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