The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 04, 2021

Filed:

Jul. 19, 2017
Applicant:

Lutonix, Inc., New Hope, MN (US);

Inventor:

Lixiao Wang, Medina, MN (US);

Assignee:

Lutonix, Inc., Franklin Lakes, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 29/16 (2006.01); A61K 31/337 (2006.01); A61K 31/436 (2006.01); A61L 31/16 (2006.01); A61L 29/08 (2006.01); A61L 31/08 (2006.01); A61L 31/10 (2006.01); A61M 25/10 (2013.01);
U.S. Cl.
CPC ...
A61L 29/16 (2013.01); A61K 31/337 (2013.01); A61K 31/436 (2013.01); A61L 29/08 (2013.01); A61L 29/085 (2013.01); A61L 31/08 (2013.01); A61L 31/10 (2013.01); A61L 31/16 (2013.01); A61M 25/10 (2013.01); A61L 2300/204 (2013.01); A61L 2300/416 (2013.01); A61L 2300/428 (2013.01); A61L 2300/606 (2013.01); A61L 2300/608 (2013.01); A61L 2300/802 (2013.01); A61L 2420/06 (2013.01); A61M 2025/105 (2013.01); A61M 2025/1075 (2013.01);
Abstract

Medical device are provided for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a therapeutic agent and an additive. In certain embodiments, the additive has a hydrophilic part and a drug affinity part, wherein the drug affinity part is at least one of a hydrophobic part, a part that has an affinity to the therapeutic agent by hydrogen bonding, and a part that has an affinity to the therapeutic agent by van der Waals interactions. In embodiments, the additive is water-soluble. In further embodiments, the additive is at least one of a surfactant and a chemical compound, and the chemical compound has a molecular weight of from 80 to 750 or has more than four hydroxyl groups.


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