The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 04, 2021
Filed:
May. 11, 2018
Applicant:
Massachusetts Institute of Technology, Cambridge, MA (US);
Inventors:
Jiahe Li, Medford, MA (US);
Paula T. Hammond, Newton, MA (US);
Yanpu He, Cambridge, MA (US);
Wade Wang, Cambridge, MA (US);
Assignee:
Massachusetts Institute of Technology, Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12N 15/113 (2010.01); A61K 9/00 (2006.01); A61K 38/17 (2006.01); A61K 47/42 (2017.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
A61K 48/005 (2013.01); A61K 9/0019 (2013.01); A61K 38/17 (2013.01); A61K 47/42 (2013.01); A61K 48/0075 (2013.01); C12N 15/111 (2013.01); C12N 15/113 (2013.01); C12N 2310/121 (2013.01); C12N 2310/122 (2013.01); C12N 2310/14 (2013.01); C12N 2310/141 (2013.01); C12N 2310/31 (2013.01); C12N 2310/333 (2013.01); C12N 2310/335 (2013.01); C12N 2310/336 (2013.01); C12N 2310/3341 (2013.01); C12N 2320/35 (2013.01);
Abstract
The invention relates to methods of improving efficacy and enhancing silencing of target genes using Ago2 protein-dsRNA complex (RNP) of the invention.