The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 04, 2021
Filed:
Dec. 04, 2019
Applicants:
Universitaetsklinikum Freiburg, Freiburg, DE;
Baker Idi Heart & Diabetes Institute Holdings Ltd., Melbourne, AU;
Inventors:
Assignees:
UNIVERSITAETSKLINIKUM FREIBURG, Freiburg, DE;
BAKER IDI HEART & DIABETES INSTITUTE HOLDINGS LTD., Melbourne, AU;
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/20 (2006.01); C12N 15/00 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61K 38/17 (2006.01); C07K 16/28 (2006.01); A61K 38/08 (2019.01); A61K 38/10 (2006.01); A61K 38/12 (2006.01); C07K 16/24 (2006.01);
U.S. Cl.
CPC ...
A61K 39/3955 (2013.01); A61K 38/08 (2013.01); A61K 38/10 (2013.01); A61K 38/12 (2013.01); A61K 38/1709 (2013.01); C07K 16/241 (2013.01); C07K 16/2845 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/70 (2013.01); C07K 2317/76 (2013.01);
Abstract
The CD40L/Mac-1 interaction is selectively targeted by small peptide inhibitors and/or antibodies and such peptides are used for the specific treatment of inflammation and atherogenesis. In particular, pharmaceutical compositions comprising a polypeptide having the amino acid sequence EQLKKSKTL and antibodies specifically binding to an epitope are disclosed.