The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 04, 2021
Filed:
Dec. 07, 2015
Applicant:
Erasmus University Medical Center Rotterdam, Rotterdam, NL;
Inventors:
Erik van der Wal, Rotterdam, NL;
Atze Jacobus Bergsma, Rotterdam, NL;
Wilhelmus Wenceslaus Matthias Pijnappel, Rotterdam, NL;
Antje Tjitske van der Ploeg, Rotterdam, NL;
Arnoldus Reuser, Rotterdam, NL;
Assignee:
Erasmus University Medical Center Rotterdam, Rotterdam, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/47 (2006.01); C12N 15/11 (2006.01); C12N 15/113 (2010.01); A61P 21/00 (2006.01); A61P 3/00 (2006.01); A61K 31/352 (2006.01);
U.S. Cl.
CPC ...
A61K 38/47 (2013.01); A61K 31/352 (2013.01); A61P 3/00 (2018.01); A61P 21/00 (2018.01); C12N 15/111 (2013.01); C12N 15/1137 (2013.01); C12Y 302/0102 (2013.01); C12N 2310/11 (2013.01); C12N 2320/33 (2013.01);
Abstract
The present invention is direct to the treatment of Pompe disease by administration of an enzyme or nucleic acid encoding for said enzyme suitable for Enzyme Replacement Therapy for Pompe disease in combination with the administration of an antisense oligomeric compound that modulates the splicing of acid alpha-glucosidase (GAA) gene.