The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 04, 2021

Filed:

Aug. 06, 2018
Applicant:

The Nemours Foundation, Jacksonville, FL (US);

Inventors:

Kenneth Andrew Alexander, Orlando, FL (US);

Terri Helman Finkel, Orlando, FL (US);

Joseph Mazar, Orlando, FL (US);

Amy Lynn Rosado, Orlando, FL (US);

Jiangfang Wang, Orlando, FL (US);

Tamarah Jeanette Westmoreland, Orlando, FL (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/768 (2015.01); C12N 7/00 (2006.01); A61P 35/00 (2006.01); A61K 35/74 (2015.01); A61K 35/76 (2015.01); C07K 14/705 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 35/768 (2013.01); A61P 35/00 (2018.01); C07K 16/2896 (2013.01); C12N 2770/24132 (2013.01);
Abstract

CD24-positive malignant and benign tumors are treated by administration of a naturally occurring or modified oncolytic Zika virus. Diseases associated with abnormal T cell activation or T cell-mediated autoimmunity, wherein CD24 expression is increased, are also expected to be treated by administration of a naturally occurring or modified oncolytic Zika virus. Also contemplated are compounds and methods for treating and/or preventing Zika virus infection in a subject.


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